Activation of HTLV-I gene transcription by protein tyrosine phosphatase inhibitors
نویسندگان
چکیده
منابع مشابه
Activation of HTLV-I gene transcription by protein tyrosine phosphatase inhibitors.
Human T-cell leukemia virus type I (HTLV-I) transcription generally depends on the ability of the viral Tax protein to bind the CREB transcription factor and form an active complex by recruiting CBP/p300 coactivators to the long terminal repeat (LTR). Studies have demonstrated that T-cell activating agents that stimulate CREB are potent inducers of HTLV-I transcription. Herein, we demonstrate t...
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ژورنال
عنوان ژورنال: Virology
سال: 2004
ISSN: 0042-6822
DOI: 10.1016/j.virol.2004.09.003